TITLE: Otoneurological manifestations of herpes virus

Abstract:

Objective. Demonstrate the presence of herpes zoster with antiviral antibodies (Ab) in patients with neuro-otological manifestations, facial paralysis, vestibulococleopathy, Vestibulopathy, as well as demonstrate the effectiveness of zovirax use for them.Introduction:The vestibular neuronitis is a degenerative neuropathy of the peripheral vestibular system. The etiology is uncertain but is believed to be of viral origin. Ramsay Hunt in the year 1907 suggested that herpes zoster otic was the result of a ganglionitis the geniculate ganglion. But many contemporary authors believe that this condition corresponds to a neuritis or polyneuropathy.

Material and methods: We selected patients of any age who attended the clinic for neuro-otological manifestations, facial paralysis, vestibular neuronitis or cochleopathy which presented clinical data compatible with viral herpetic infection to which we took panels of antiviral antibodies against herpes 1 , varicella zoster or herpes 2 to which of them was treated with Zovirax. And their behavior was monitored clinical neuro-otological diagnosis was made by neuro-otological studies or electromyography as the case merited. Pathologies were separated Cochlear, vestibular, facial, and vestibulofacial and cochleofacial, vestibulocochlear for study and classification.

Results.A total of 16 patients within 2 years 7 men and 9 women, of whom 6 had cochlear manifestations, 10 had vestibular manifestations, 5 had facial expressions, 3 had vestibulocochlear manifestations, demonstrations presented vestibulofacial 1, 1 present manifestations cocleofacial.Of the 16 patients 11 were positive for IgG VH1 pair, 6 were positive for IgM VH1, 3 were positive for VH2IgG, 2 with VH2IgM, 15 with Varicella IgG, 2 with IgM Varicella.

Conclusions:We found a higher incidence in female than male patients, the pathologies that occurs most frequently were Vestibulopathy. Most of the cases had positive IgG implying reinfection or reactivation of previous pathology in 15 of the 16 cases tested positive varicella antiviral antibodies. As for the more rapid clinical response was initiated faster Zovirax treatment was resolution of clinical manifestations.

PARALISIS FACIAL, VERTIGO Y ACUFENO EN RELACION A VIRUS DEL HERPES ZOSTER.

http://www.medigraphic.com/pdfs/anaotomex/aom-2004/aom044g.pdf

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